解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Analysis of the partition in a two-polymer phase system of Salmonella typhimurium R mutants with different susceptibility to phagocytosis distinguished between the mutants. Close to 80% of the R mutants least resistant to phagocytosis accumulated in the dextran-rich phase, whereas more phagocytosis-resistant mutants s...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.8.1.36-41.1973
更新日期:1973-07-01 00:00:00
abstract::Humoral and cellular immune responses to several antigens were compared in control and hypercholesterolemic groups of monkeys. Chronic hypercholesterolemia, with concomitant hyperphospholipidemia and hypotriglyceridemia, was produced experimentally by feeding monkeys a high-fat, high-cholesterol diet. When studied pri...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.8.1.105-109.1973
更新日期:1973-07-01 00:00:00
abstract::Subpopulations of spleen cells from scrapie virus-infected mice were used to determine the average virus content of infected cells in vivo at a time when virus was rapidly increasing in titer in lymphoreticular tissues. Comparison of the mean lethal doses of lysed to intact cells indicated averages of 2 to 6 infectiou...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.6.918-921.1973
更新日期:1973-06-01 00:00:00
abstract::Mycoplasma hyorhinis organisms were fractionated into lipid, carbohydrate, and protein fractions by chemical and physiochemical procedures. When all fractions were tested for complement fixation and inhibition of growth inhibition activity, only the protein fractions possessed activity. Thus, it appears that the major...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.6.937-940.1973
更新日期:1973-06-01 00:00:00
abstract::Sensitized mouse spleen cells decrease the spread of herpes simplex virus infection in cell culture lines derived from human and murine tissues. These washed, sensitized cells act alone and additively in combination with antibody to diminish the ability of single virus-infected cells to spread infection to contiguous ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.6.898-904.1973
更新日期:1973-06-01 00:00:00
abstract::At least 10 of 11 demonstrable antigens in unheated culture filtrates of 12 vaccine strains of BCG were shared as determined in a reference antigen-antibody immunoelectrophoresis system. Filtrates from each of the BCG strains gave equivalent skin test reactions in homologously and heterologously sensitized guinea pigs...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.5.777-780.1973
更新日期:1973-05-01 00:00:00
abstract::Endocarditis was induced in the rabbit by the placement of a polyethylene catheter in the right heart. The catheter was filled with stable L-phase variants of Staphylococcus aureus to determine if the variant form would colonize the damaged endocardium and produce further tissue injury similar to that produced by the ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.5.725-730.1973
更新日期:1973-05-01 00:00:00
abstract::Administration of a standard bacterial vaccine (SBV) affords some protection against influenza infection in mice if given 4 to 5 h before inoculation of the virus. This effect was enhanced by repeated injections of SBV 7 and 14 days earlier, as measured by the length of survival, mortality rate, development of gross p...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.5.771-776.1973
更新日期:1973-05-01 00:00:00
abstract::The effects of treatment with live or inactivated Shope fibroma virus on host cell deoxyribonucleic acid (DNA) synthesis were determined. The incorporation of (3)H-thymidine into nuclear DNA was suppressed by both active and inactivated virus, although live virus was more effective. During the early phase of infection...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.4.532-538.1973
更新日期:1973-04-01 00:00:00
abstract::Conjunctival infection of guinea pigs by the chlamydial agent of guinea pig inclusion conjunctivitis confers immunity. However, the mechanism of resistance to this intracellular pathogen is not yet defined. In the study reported here, serum immunoglobulin was passively transferred with resultant titers in excess of th...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.4.597-599.1973
更新日期:1973-04-01 00:00:00
abstract::An experimental model of "chronic" diphtheria intoxication in the guinea pig was developed. Adult guinea pigs, subjected to a regimen of multiple sublethal doses of purified diphtheria toxin (total of 1.4 minimum lethal doses divided equally in four daily doses), developed a toxemia which terminated in death between 6...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.4.556-560.1973
更新日期:1973-04-01 00:00:00
abstract::In assessing the host cell range of bovine parvoviruses, these viruses were found to replicate optimally in actively dividing bovine fetal lung and spleen cells. Other primary bovine fetal cells supported growth to a lesser extent, but bovine line cells and line cells of other animal species tested did not. Minimal in...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.3.398-402.1973
更新日期:1973-03-01 00:00:00
abstract::Antibodies against mumps virus have been studied by using immunoglobulin class-specific indicators labeled with (125)I in the radioimmunoassay (RIA) procedure. The immunoglobulins in paired acute and convalescent sera were allowed to react with mumps virus in a solid-phase RIA system. Class-specific immunoglobulin ind...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.3.380-385.1973
更新日期:1973-03-01 00:00:00
abstract::A comparison of viral-induced unresponsiveness of phytohemagglutinin (PHA)-induced deoxyribonucleic acid (DNA) synthesis of mouse lymphocytes was made by culturing the cells under identical conditions in the presence of HEPES buffer in a humid-air atmosphere. The degree of PHA-induced DNA synthesis was found to vary, ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.3.438-444.1973
更新日期:1973-03-01 00:00:00
abstract::The guinea pig migration inhibition technique, an accepted in vitro correlate of delayed hypersensitivity, has been adapted to a murine system. Peritoneal exudate cells from CF-1 mice vaccinated with viable cells of the H37Ra strain of Mycobacterium tuberculosis were inhibited in vitro by purified protein derivative (...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.2.190-195.1973
更新日期:1973-02-01 00:00:00
abstract::The effects of infection with Rowson-Parr virus (RPV), an associated virus present in Friend virus (FV) preparations, on the splenic plaque-forming cell response to sheep red cells in adult mice and on the plaque-forming cell response of peritoneal cells in vitro have been investigated. The results support the hypothe...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.2.160-166.1973
更新日期:1973-02-01 00:00:00
abstract::Guinea pigs sensitized by repeated skin testing with potent, merthiolated coccidioidin, equal to Smith standard, exhibited erythema, edema, and an induration-like reaction to intradermal injection of the preparation. No statistically significant migration inhibition of peritoneal exudate macrophages from these animals...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.2.226-230.1973
更新日期:1973-02-01 00:00:00
abstract::Utilization of the technique of immune electron microscopy has enabled the detection of a coronavirus in organ culture harvests derived from a washing from an adult with an acute upper respiratory tract illness; convalescent serum was the source of specific antibody. ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.1.111-116.1973
更新日期:1973-01-01 00:00:00
abstract::The purpose of these experiments was to study the early response of mouse foot pads to Mycobacterium leprae. To accomplish this, mice were inoculated in both foot pads with large and small numbers of organisms. The animals were sacrificed at intervals from 2 hr to 27 days after inoculation. The microscopical results, ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.1.76-85.1973
更新日期:1973-01-01 00:00:00
abstract::Sephadex G-200 filtration was used for fractionating dengue type 2 (DEN-2)-infected suckling mouse brain (SMB) supernatant fluids. The high-molecular-weight fraction, which was eluted in the void volume, showed no increase in type specificity when tested against immune ascitic fluid to the four prototype dengue viruse...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.6.952-957.1972
更新日期:1972-12-01 00:00:00
abstract::A cell wall complex has been isolated by gentle methods from both the medium supernatant fluid and whole organisms of Neissieria meningitidis cultures. The two types of preparations have been shown to be essentially identical on the basis of chemical composition, electron microscopy, and polyacrylamide gel electrophor...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.5.835-851.1972
更新日期:1972-11-01 00:00:00
abstract::Exfoliatin caused skin loss in hairless mutant mice only while they lacked hair, but older mice were more resistant to this effect than neonates. ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.5.877-879.1972
更新日期:1972-11-01 00:00:00
abstract::Formation of compact colonies of Staphylococcus aureus in serum-soft agar is mainly a result of a reaction between protein A and the Fc-part of immunoglobulin G and not a clumping factor-fibrinogen reaction. ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.4.583-586.1972
更新日期:1972-10-01 00:00:00
abstract::The porcine immunoglobulins M (IgM), A (IgA), and G (IgG) were isolated and purified and some of the properties of the porcine milk IgA were examined. Monospecific antisera which were prepared against these immunoglobulins in rabbits were then used to absorb a particular class of immunoglobulin from sow serum, colostr...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.4.600-609.1972
更新日期:1972-10-01 00:00:00
abstract::In vitro, macrophages from normal strain BRVR mice killed Salmonella more quickly than did macrophages from normal strain BSVS mice. Salmonella injected intraperitoneally multiplied more quickly in BSVS mice than in BRVR mice. BRVR macrophages injected intraperitoneally into BSVS mice protected against Salmonella mult...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.4.438-443.1972
更新日期:1972-10-01 00:00:00
abstract::Whole cells, morphological components, and various extracts of Candida albicans were tested for toxicity by methods involving biological activities ordinarily used to characterize bacterial endotoxin. Fungal preparations exerted several of these activities, but only at much higher dose levels than those required for b...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.4.616-627.1972
更新日期:1972-10-01 00:00:00
abstract::Ribosomes of strain NOR-7 of group B Neisseria meningitidis were isolated by a procedure that included treatment of the cells with sodium dodecyl sulfate, disruption in a French pressure cell, and differential centrifugation. These preparations consisted of 66% ribonucleic acid and 24% protein and sedimented as a sing...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.3.355-363.1972
更新日期:1972-09-01 00:00:00
abstract::Transplacental infection of mouse fetuses with Venezuelan equine encephalomyelitis was produced by intraperitoneal injection of dams at various stages of gestation with 10(3) suckling mouse intracerebral median lethal doses of an attenuated strain (TC-83). Virus inoculation, at times ranging from 6 days prior to matin...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.3.339-343.1972
更新日期:1972-09-01 00:00:00
abstract::Mice immunized subcutaneously with heat-killed Escherichia coli were protected from pyelonephritis produced by the intravenous route, but there was little or no protection from ascending infection. No significant protection from ascending or hematogenous pyelonephritis was demonstrated when immunization was accomplish...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.3.330-334.1972
更新日期:1972-09-01 00:00:00
abstract::Earlier work had shown that a collection of anaerobic bacteria, in conjunction with facultative anaerobes, may be implanted into germfree mice, thereby rendering the animals "normal" with respect to a variety of parameters tested. The present experiments indicate that a different collection of anaerobic bacteria, isol...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.2.119-126.1972
更新日期:1972-08-01 00:00:00
abstract::The lungs of conventional rats with chronic pneumonia contained Streptobacillus moniliformis and Mycoplasma pulmonis. These organisms singly and in combination failed to produce lung disease when inoculated into specific pathogen-free rats. On the other hand, diseased lung homogenate not containing cultivable organism...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.6.1.83-91.1972
更新日期:1972-07-01 00:00:00
abstract::Little data are available regarding L-form phagocyte interactions. Due to difficulty with more conventional methods, a serum-free technique of surface phagocytosis employing cellulose ester micropore filters, fluorochrome staining, and reflecting fluorescence microscopy was developed. Intracellular localization of L-f...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.6.976-981.1972
更新日期:1972-06-01 00:00:00
abstract::A plaque assay system for pathogenic rickettsiae, which utilizes primary chick embryo tissue cultures, is described. It proved to be a highly reproducible measure of infectiousness for Rickettsia rickettsi and R. typhi, which were employed in most studies; as well as for R. canada, R. prowazeki, R. sibirica, R. akari,...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.5.715-722.1972
更新日期:1972-05-01 00:00:00
abstract::Naturally occurring antibodies for Vibrio fetus with whole-cell and O antigen specificities were detected in sera of mature cattle by means of the agglutination and indirect immunofluorescence reactions. O antibodies occurred in each of 21 sera examined, and whole-cell antibodies, in lower concentrations, occurred in ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.5.728-733.1972
更新日期:1972-05-01 00:00:00
abstract::Two enteropathogenic strains of Escherichia coli (EEC) differed from a nonenteropathogenic strain of E. coli (NEEC) in their association with porcine small intestinal epithelium. The EEC characteristically were found along villi from tip to base and contiguous to the brush border. They were not in crypts. In contrast,...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.4.595-605.1972
更新日期:1972-04-01 00:00:00
abstract::Feline leukemia-sarcoma group-specific antigens were located in human embryo cells infected with feline leukemia and feline sarcoma viruses. This was done by using the fluorescent-antibody and enzyme-labeled antibody techniques at both light and electron microscopic levels. The antigens were found to be exclusively in...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.3.400-405.1972
更新日期:1972-03-01 00:00:00
abstract::Lymphocytes derived from 72- to 90-day-old fetal piglet thymuses respond in vitro to phytohemagglutinin quantitatively greater than do spleen cell lymphocytes. ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.3.337-338.1972
更新日期:1972-03-01 00:00:00
abstract::The relationship between hypersensitivity and cellular resistance to infection with facultative intracellular parasites was studied in mice by using infection-immunity in tularemia as a model system. Delayed hypersensitivity to antigenic fractions of Francisella tularensis was first detected 6 to 7 days after immuniza...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.3.311-318.1972
更新日期:1972-03-01 00:00:00
abstract::The effects of temperature and treatment with sodium dodecyl sulfate, Tween 20, dithiothreitol, trypsin, or guanidine on the hemagglutinating capacity of six strains of type A influenza virus (A(0)/PR8/34, A(1)/CAME/46, A(2)/J305/57, A(2)/Bethesda/63, A(2)/HK/Aichi/68, and A(2)/HK/80/68), one strain of swine virus (A/...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.3.324-331.1972
更新日期:1972-03-01 00:00:00
abstract::Radial immunodiffusion procedures have been developed for testing bovine sera for the presence of antibody activity against three foot-and-mouth disease virus types and a virus infection-associated antigen. Reactions with virus antigens were obtained as early as 4 days after infection, and the virus type causing the r...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.5.2.227-231.1972
更新日期:1972-02-01 00:00:00